Relationship among latitude, climate, season and self-reported mood in
bipolar disorder
Journal of Affective Disorders, 06/10/09
- Bauer M et al. - Daily self-reported mood ratings of most patients with bipolar disorder did not show a seasonal pattern. Neither climate nor latitude has a primary influence on the daily mood changes of most patients receiving medication for bipolar disorder.
- 360 patients who were receiving treatment as usual recorded mood daily (59,422 total days of data).
- Both the percentage of days depressed and hypomanic/manic, and the episodes of depression and mania were determined.
- The observations were provided by patients from different geographic locations in North and South America, Europe and Australia.
- These data were analyzed for seasonality by climate zone using both a sinusoidal regression and the Gini index.
- Additionally, the influence of latitude and climate variables on mood was estimated using generalized linear models for each season and month.
- No seasonality was found in any climate zone by either method.
- In spite of vastly different weather, neither latitude nor climate variables were associated with mood by season or month.
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