PSIHOSTIMULANTE IN M A N I E

Are Psychostimulants a Treatment Option in Mania
Pharmacopsychiatry, 09/04/09 Hegerl U et al. – Mania and attention–deficit hyperactivity disorder (ADHD) show a high degree of symptom overlap and comorbidity. Clinical trials and case reports indicate that psychostimulants do not or only rarely trigger or aggravate manic episodes but can even produce rapid and pronounced antimanic effects. An explanatory model is presented here in which the sensation seeking, hyperactive behaviour observed in mania and ADHD is interpreted as an autoregulatory attempt to stabilize vigilance by increasing external stimulation.