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*Polycystic Ovary Syndrome, Obesity and Reproductive Implications CME

Angelica Lindén Hirschberg, MD, PhD

CME Released: 08/24/2009; Valid for credit through 08/24/2010

Target Audience

This activity is intended for primary care clinicians, obstetricians and gynecologists, endocrinologists, and other specialists who care for women.

Goal

The goal of this activity is to review the clinical criteria for diagnosing polycystic ovary syndrome and its complications and management strategies.

Authors and Disclosures

Angelica Lindén Hirschberg, MD, PhD
Department of Woman & Child Health, Division of Obstetrics & Gynecology, Karolinska Institutet, Stockholm, Sweden
Disclosure: Angelica Lindén Hirschberg, MD, PhD, has disclosed no relevant financial relationships.

Elisa Manzotti
Editorial Director, Future Science Group, London, United Kingdom
Disclosure: Elisa Manzotti has disclosed no relevant financial relationships.

Désirée Lie, MD, MSEd
Clinical Professor, Family Medicine, University of California, Orange; Director, Division of Faculty Development, UCI Medical Center, Orange, California
Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships.

Learning Objectives

Upon completion of this activity, participants will be able to:

Describe the diagnostic criteria for polycystic ovary syndrome (PCOS)
Identify clinical consequences of androgen excess in women with PCOS
Describe long-term risks associated with PCOS
Describe the effects of PCOS on pregnancy outcomes
Describe the effect of metformin on PCOS

Credits Available

Physicians - maximum of 0.75 AMA PRA Category 1 Credit(s)™

All other healthcare professionals completing continuing education credit for this activity will be issued a certificate of participation.

Physicians should only claim credit commensurate with the extent of their participation in the activity.

Accreditation Statements

For Physicians

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of MedscapeCME and Future Medicine Ltd.

MedscapeCME is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

MedscapeCME designates this educational activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™ . Physicians should only claim credit commensurate with the extent of their participation in the activity.

Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact CME@medscape.net

CME Released: 08/24/2009; Valid for credit through 08/24/2010

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page.

Follow these steps to earn CME/CE credit*:

Read the target audience, learning objectives, and author disclosures.
Study the educational content online or printed out.
Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. MedscapeCME encourages you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of your Medscape homepage.

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Abstract and Introduction

Abstract-rev.endocrin.

Polycystic ovary syndrome (PCOS) is one of the most common causes of female infertility, affecting 5-10% of women of reproductive age. The syndrome is characterized by anovulation, hyperandrogenism and polycystic ovaries. Furthermore, PCOS is associated with insulin resistance and obesity, which is present in approximately 50% of women with PCOS. Reproductive function in women with PCOS is strongly dependent on bodyweight and metabolic status. Obesity is associated with an increased risk of infertility and may also have a negative influence on pregnancy outcome. Considering the worldwide epidemic of obesity, clinical problems relating to PCOS may worsen and increase in frequency. Lifestyle interventions resulting in weight loss comprise the most successful strategy to improve symptoms of PCOS. However, many patients fail to lose weight or may quickly regain weight. It is an important challenge to develop effective lifestyle programs and adjuvant pharmacologic treatments in order to improve reproductive and metabolic health among women with PCOS