Up to date on Diagnosis and Treatment

* Persistent job insecurity poses a major threat to worker health, according to a new study published in the September issue of the peer–reviewed journal Social Science and Medicine.

 

 

* A Psychoneuroendocrinology Service
Psychotherapy and Psychosomatics, 08/31/09

Sonino N et al. – In the highly selected population, several difficult patients could be appropriately managed by virtue of a holistic view. Such an approach must involve experienced clinicians with a broad–spectrum training in psychoneuroendocrinology and psychosomatic medicine. If confirmed in its efficacy and cost–effectiveness, this model might be further expanded.

 

 

 

* Are cholinesterase inhibitors effective in the management of the behavioral and psychological symptoms of dementia in Alzheimers disease? A systematic review of randomized, placebo-controlled trials of donepezil, rivastigmine and galantamine
International Psychogeriatrics, 08/31/09

Rodda J et al. – The evidence base regarding the efficacy of cholinesterase inhibitors in BPSD is limited, in part due to methodological considerations. In the absence of alternative safe and effective management options, the use of cholinesterase inhibitors is an appropriate pharmacological strategy for the management of BPSD in Alzheimer's disease.

 

 

 

* deprsia tratata cu olanzapine plus zoloft

Treatment with olanzapine/sertraline was associated with higher remission rates during the trial than olanzapine/placebo (odds ratio [OR], 1.28; 95% confidence interval [CI], 1.12–1.47; P < .001

* propunere de noua entitate

Purging Disorder a diagnosis on equal footing with Anorexia Nervosa and Bulimia Nervosa .

* * vagabatrin in dependenta cocainica

Brodie JD et al. – This first randomized, double–blind, placebo–controlled trial supports the safety and efficacy of short–term vigabatrin treatment of cocaine dependence .

* lipsa educatiei favorizeaza dementa

Low–education is associated with dementia and female–gender with AD .

* stresul psihogen

When you feel ill or imbalanced, treating your whole self rather than treating the physical self alone can empower you to determine the root cause of sickness. Since you understand that your physical symptoms may be an expression of emotional discomfort, you can establish a balanced treatment regimen to ensure that you quickly recover your good health.

* ai grija

It has been said that if you treat yourself well, the world will treat you even better. Check out these quotes and affirmations meant to inspire you toward a better self-image.
 

* se poate preveni dementa

Activities that exercise the brain, such as reading, writing, and playing games, might help patients postpone the cognitive decline associated with dementi

* stresul psihogen

When you feel ill or imbalanced, treating your whole self rather than treating the physical self alone can empower you to determine the root cause of sickness. Since you understand that your physical symptoms may be an expression of emotional discomfort, you can establish a balanced treatment regimen to ensure that you quickly recover your good health.

* nou:lloperidol

  • The oral formulation has demonstrated efficacy in reducing the symptoms of acute schizophrenia at fixed daily doses ranging from 12 to 24 mg.
  • Iloperidone should be titrated slowly to avoid orthostatic hypotension, potentially delaying the achievement of a therapeutic dose level.
  • There appears to be a dose relationship for adverse events such as dizziness, somnolence and dry mouth; for example NNH vs. placebo for somnolence was 25 for iloperidone 10–16 mg/day and 10 for 20–24 mg/day.
  • Iloperidone is essentially free of extra-pyramidal side effects.
  • Iloperidone is associated with weight gain comparable with risperidone.
  • Long-term double-blind maintenance studies have demonstrated iloperidone's non-inferiority to haloperidol for relapse prevention.
  • Product labelling includes a warning about the potential for QT interval prolongation.
  • The development of a depot formulation of iloperidone as well as efforts to identify genetic biomarkers for prediction of both efficacy and tolerability are in progress.

 

 

* dieta cu f i b r e

August 10, 2009 —- Dietary fiber is linked to a reduced risk for type 2 diabetes, which may be partly explained by inflammatory markers and hepatic fat deposition, according to the results of a prospective study reported ahead of print in the July 23 issue of Diabetes Care

 

 

 

 

* valproat in psihozele afective

At the genetic level, growing data suggest that the long–term treatment of mood disorders may involve the regulation of signalling pathways and gene expression in critical neuronal circuits.

 

 

 

* e posibil

You can free yourself from aging by reinterpreting your body and by grasping the link between belief and biology."

* efecte secundare

  • Bupropion and duloxetine caused significantly less sexual dysfunction than the SSRIs in short–term studies and reboxetine significantly less in both short– and longer term studies.
  • Bupropion and agomelatine caused significantly less sexual dysfunction than venlafaxine.
  • The evidence for mirtazepine having an advantage over the SSRIs is lacking and there are currently insufficient data for desvenlafaxine.
  • Well–designed comparative studies of contemporary antidepressants with direct assessment of sexual side–effects as the primary outcome measure are scarce.

 

 

 

* substratul antomo-patologic al schizofreniei

Chan RCK et al. – Frontotemporal brain structural abnormalities are evident in nonpsychotic individuals at high risk of developing schizophrenia. The present meta–analysis indicates that these gray matter abnormalities become more extensive through first–episode and chronic illness. Thus, schizophrenia appears to be a progressive cortico–striato–thalamic loop disorder.

* nevroza obsesionala

Pessina E et al, – This study supports the notion that adding aripiprazole to SRIs could be a valid strategy for treatment–resistant OCD patients, and points towards the need of randomized, double–blind studies.

* exercitu fizic antipanica

in addition to exercise training an acute bout of exercise may be used to reduce anxiety and panic attack frequency and intensity in panic disorder patients.

* conteaza si materia alba

Theory of mind age–related decline may not be independent of other cognitive functions; it may also be particularly susceptible to changes in white matter integrity.

* sch+alcool+drog=violenta

A study demonstrates that there is an association between schizophrenia and violence, but shows that this association is greatly increased by drug and alcohol abuse.

* mincatul creste la tratamentul cu antipsihotice second generation

Results
  • Did not find any difference according to sex, but the mean body mass index varied significantly among the three groups of patients.
  • The DEBQ external eating factor was higher in patients treated with atypical antipsychotics than in patients who received conventional neuroleptics (P=0.035).
  • The TFEQ disinhibition and DEBQ emotional eating scores tended to change among the three types of treatment.
  • Patients with metabolic syndrome (19%) had lower DEBQ external eating scores (P=0.044) and a tendency of higher TFEQ disinhibition scores.
  • The TFEQ disinhibition and hunger scores increased according to the body mass index (P=0.003; P=0.017).

 

 

 

 

 

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