MDLinx - New Interesting Articles

Your Article Summary Cognitive Behavior Therapy for Schizophrenia and Psychosis: Current Status and Future Directions (>> click to go to the journal's website) Clinical Schizophrenia & Related Psychoses, 11/02/10

Tarrier N – Cognitive behavior therapy (CBT) is an empirically based psychological treatment, which has a strong evidence base in a range of psychological disorders and, more recently, has also been applied to more serious disorders such as schizophrenia and psychoses (CBTp). Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list Levomepromazine for schizophrenia Cochrane Reviews, 10/26/10 Paternal age at birth of first child and risk of schizophrenia American Journal of Psychiatry, 10/20/10 Peripheral oxytocin is associated with reduced symptom severity in schizophrenia Schizophrenia Research, 10/19/10

 

 

Your Article Summary Effect of a Motivational Intervention on Exercise Behavior in Persons with Schizophrenia Spectrum Disorders (>> click to go to the journal's website) Community Mental Health Journal, 11/29/10

Beebe LH et al. – Ninety seven outpatients with schizophrenia spectrum disorders (SSDs) were randomly assigned to the Walk, Address Sensations, Learn About Exercise, Cue Exercise Behavior for SSDs (WALC–S), a motivational intervention designed to increase exercise in SSDs (n = 48), or a time and attention control group (TAC, n = 49). This study is among the first to examine interventions designed to enhance exercise motivation in SSDs. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list Paternal age at birth of first child and risk of schizophrenia American Journal of Psychiatry, 10/20/10 Thyroid gland and cerebella lesions: New risk factors for sudden cardiac death in schizophrenia Medical Hypotheses, 11/12/10 Lower Mortality Among Stroke Patients With Schizophrenia: A Nationwide Population-Based Study Psychosomatic Medicine, 11/04/10

 

 

Your Article Summary Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review (>> click to go to the journal's website) Nutrition Journal, 10/08/10

Lakhan SE et al. – Based on the available evidence, it appears that nutritional and herbal supplementation is an effective method for treating anxiety and anxiety–related conditions without the risk of serious side effects. There is the possibility that any positive effects seen could be due to a placebo effect, which may have a significant psychological impact on participants with mental disorders. However, based on this systematic review, strong evidence exists for the use of herbal supplements containing extracts of passionflower or kava and combinations of L–lysine and L–arginine as treatments for anxiety symptoms and disorders. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Smelling Chemosensory Signals of Males in Anxious Versus Nonanxious Condition Increases State Anxiety of Female Subjects Chemical Senses, 10/12/10 Psychotropic medication use mediates the relationship between mood and anxiety disorders and obesity: Findings from a nationally representative sample Journal of Psychiatric Research, 11/05/10 Shame- and guilt-proneness: Relationships with anxiety disorder symptoms in a clinical sample Journal of Anxiety Disorders, 11/03/10

 

Your Article Summary Topiramate for the Treatment of Alcohol Dependence: Comparison with Naltrexone (>> click to go to the journal's website) European Addiction Research, 10/28/10

Florez G et al. – Topiramate at a mean dose of 200 mg/day was better than naltrexone at a mean dose of 50 mg/day at reducing alcohol intake and cravings throughout the study. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list An Assessment of the Demographic and Clinical Correlates of the Dimensions of Alcohol Use Behaviour Alcohol and Alcoholism , 09/30/10 Discrepancy between how children perceive their own alcohol risk and how they perceive alcohol risk for other children longitudinally predicts alcohol use Addictive Behaviours, 10/04/10 Increase in Alcohol Intake, Reduced Flexibility of Alcohol Drinking, and Evidence of Signs of Alcohol Intoxication in Sardinian Alcohol-Preferring model Exposed to Intermittent Access to 20% Alcohol Alcoholism, 09/29/10

 

Your Article Summary Milnacipran: a unique antidepressant? (>> click to go to the journal's website) Neuropsychiatric Disease and Treatment, 08/27/10

Kasper S et al. – Milnacipran, one of the pioneer serotonin reuptake inhibitors (SSRIs), was designed from theoretic considerations to be more effective than SSRIs and better tolerated than Tricyclic antidepressants (TCAs), and with a simple pharmacokinetic profile. Milnacipran has the most balanced potency ratio for reuptake inhibition of the two neurotransmitters compared with other SNRIs (1:1.6 for milnacipran, 1:10 for duloxetine, and 1:30 for venlafaxine), and in some studies milnacipran has been shown to inhibit norepinephrine uptake with greater potency than serotonin (2.2:1). Clinical studies have shown that milnacipran has efficacy comparable with the TCAs and is superior to SSRIs in severe depression. In addition, milnacipran is well tolerated, with a low potential for pharmacokinetic drug?drug interactions. Milnacipran is a first–line therapy suitable for most depressed patients. It is frequently successful when other treatments fail for reasons of efficacy or tolerability. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list Antidepressant use and colorectal cancer risk: A Danish population-based case control study British Journal of Cancer, 10/06/10 Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes: a randomized, double-blind, placebo-controlled trial Menopause, 10/27/10 Selective Serotonin Reuptake Inhibitor Suppression of HIV Infectivity and Replication Psychosomatic Medicine, 10/20/10

 

Your Article Summary Treatment of Chronic Migraine (>> click to go to the journal's website) Current Pain and Headache Reports, 11/22/10

Diener HS et al. – Chronic migraine is defined in different ways. The most commonly used definition is headache on more than 15 days per month in patients with migraine. Chronic migraine is difficult to treat and requires a multidisciplinary approach. Only two pharmacological treatments have been shown to be effective in placebo–controlled randomized trials: topiramate and local injection of botulinum toxin. Both therapies are effective in patients with chronic migraine with and without medication overuse. Many other substances have been investigated in chronic daily headache. All trials were underpowered and, therefore, recommendations concerning possible efficacy are not possible. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Chronic Migraine: Epidemiology and Disease Burden Current Pain and Headache Reports, 11/19/10 Behavioral treatment programme contributes to normalization of contingent negative variation in children with migraine Cephalalgia, 11/16/10 Allergy and Immunotherapy: Are They Related to Migraine Headache Headache: The Journal of Head and Face Pain, 11/12/10

 

Your Article Summary Efficacy of music therapy treatment based on cycles of sessions: A randomised controlled trial (>> click to go to the journal's website) Aging and Mental Health, 11/22/10

Raglio A et al. – The analysis of single Neuropsychiatry Inventory (NPI) items shows that delusions, agitation and apathy significantly improved in the experimental, but not in the control group. This study suggests the effectiveness of music therapy (MT) approach with working cycles in reducing behavioural disorders of severely demented patients. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Music therapy in the context of palliative care in Tanzania International Journal of Palliative Nursing, 10/29/10 Hormone Therapy Increases Risk Of Ovarian Cancer Ivanhoe, 11/11/10 Home-based music therapy - a systematic overview of settings and conditions for an innovative service in healthcare BMC Health Services Research, 11/04/10

 

 

Your Article Summary Quality of life of people with schizophrenia, bipolar disorder and other psychotic disorders (>> click to go to the journal's website) British Journal of Psychiatry, 11/10/10

Saarni SI et al. – Depressive symptoms are the strongest predictors of poor quality of life (QoL)/health–related quality of life (HRQoL) in psychotic disorders. Subjective loss of QoL associated with psychotic disorders may be smaller than objective loss of functioning suggests. The EQ?5D is problematic as an outcome measure in psychotic disorders. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list Paternal age at birth of first child and risk of schizophrenia American Journal of Psychiatry, 10/20/10 Lower Mortality Among Stroke Patients With Schizophrenia: A Nationwide Population-Based Study Psychosomatic Medicine, 11/04/10 Clinical correlates of thalamus volume deficits in anti-psychotic-naive schizophrenia patients: A 3-Tesla MRI study Indian Journal of Psychiatry, 10/26/10

 

Your Article Summary To be grandiose or not to be worthless: Different routes to self-enhancement for narcissism and self-esteem (>> click to go to the journal's website) Journal of Research in Personality, 11/11/10

Horvath S et al. – Individuals with genuine high self–esteem in contrast, self–presented more moderately and also used the more socially accepted discounting of negative traits. Subsequent increased accessibility of positive self–information, only shown by narcissists, indicates that their desire for self–worth is hard to fulfill. These findings continue to illuminate the distinction between narcissism and self–esteem. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Psychiatry >> Click here to see the complete list Acceptability of the Talking Touchscreen for Health Literacy Assessment Journal of Health Communication, 10/29/10 The relational turn in psychoanalysis: revolution or regression European Journal of Psychotherapy, Counselling & Health, 11/03/10 Acute Pancreatitis with an Emphasis on Infection Infectious Disease Clinics of North America, 10/29/10

 

 

Your Article Summary Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial (>> click to go to the journal's website) The Lancet Neurology, 09/29/10

Emre M et al. – Memantine seems to improve global clinical status and behavioural symptoms of patients with mild to moderate dementia with Lewy bodies, and might be an option for treatment of these patients. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Cerebrovascular risk factors in early-onset dementia Journal of Neurology, Neurosurgery, and Psychiatry , 10/15/10 Worldwide Dementia Costs Reach $604 Billion First Report Managed Care, 10/27/10 Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementias Journal of Neurology, Neurosurgery, and Psychiatry , 10/18/10

 

Your Article Summary Atherosclerosis and incident depression in late life (>> click to go to the journal's website) Archives of General Psychiatry, 11/03/10

Newson RS et al. ? Atherosclerosis does not appear to increase the risk of incident depression in older adults. These findings do not support the vascular depression hypothesis and, alternatively, taking findings from prior studies into account, suggest either that depression contributes to vascular burden or that both result from an underlying biological substrate. Methods Prospective, population-based study Set within Rotterdam study, participants were assessed on objective measures of generalized atherosclerosis at baseline (1997-1999) and followed up for an average of 6 years for incident depression Baseline sample consisted of 3564 participants (56% female) with mean age of 72 years who initially did not have depression or dementia Depression categorized into symptoms or syndromes and assessed in a multidimensional manner from physician and mental health specialist reports, pharmacy records (antidepressant usage), a clinical interview, and self-report Results During 21 083 person-years, 429 incidents of depressive symptoms and 197 incidents of depressive syndromes occurred Individual atherosclerotic measures and a composite measure not predictive of incident depressive symptoms (composite measure HR, 0.93; 95% CI, 0.83-1.05) or incident depressive syndromes (composite measure HR, 0.97; 95% CI, 0.81-1.16) Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Depressive symptoms and executive functioning in stroke patients: A follow-up study International Journal of Geriatric Psychiatry, 10/27/10 Predictors of incident major depression in diabetic outpatients with subthreshold depression Diabetic Medicine, 10/26/10 Association of high-sensitivity C-reactive protein with de novo major depression British Journal of Psychiatry, 11/03/10

 

Your Article Summary Comorbidities and factors related to discontinuation of pharmacotherapy among outpatients with major depressive disorder (>> click to go to the journal's website) Comprehensive Psychiatry, 11/10/10

Hung CI et al. ? The impact of the duration of depression (chronic depression) on adherence may be more important than the severity of depression, anxiety comorbidities, and migraine. Education of MDD patients and society in general to improve understanding of MDD and antidepressants is needed to enhance adherence to pharmacotherapy. Methods 135 subjects (34 men, 101 women) with MDD enrolled MDD and anxiety comorbidities diagnosed using Structured Clinical Interview for DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision), migraine diagnosed based on International Classification of Headache Disorders, 2nd Edition, and depression severity evaluated using Hamilton Depression Rating Scale Results Subjects with chronic depression, migraine, panic/agoraphobia, or posttraumatic stress disorder attended follow-up for longer before discontinuation than those without Chronic depression and greater age independently predicted longer follow-up before discontinuation. Concern about and intolerance of SE of antidepressants and lack of insight into MDD independently predicted discontinuation within 2 months Concern about and intolerance of SE of antidepressants and lack of insight into MDD independently predicted discontinuation within 2 months ?Self-reported recovery? was most common reason for discontinuation; however, 53.8% of subjects who cited this reason did not reach full remission Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Association of high-sensitivity C-reactive protein with de novo major depression British Journal of Psychiatry, 11/03/10 Recovery and recurrence following treatment for adolescent major depression Archives of General Psychiatry, 11/04/10 Plasma homocysteine levels and major depressive disorders in Alzheimer disease American Journal of Geriatric Psychiatry, 10/27/10

 

Your Article Summary Pirlindole in the Treatment of Depression: A Meta-Analysis (>> click to go to the journal's website) Clinical Drug Investigation, 11/16/10

Macedo A – This systematic review and meta–analysis showed that all randomized controlled trials included reported efficacy outcomes for pirlindole comparable to those of its comparators, and that pirlindole was significantly better in terms of reducing anxiety symptoms. However, the analysis of these results should take into account the quality of the original included articles, which had a mean Jadad trial quality score of 3.7 (out of 5). Therefore, further clinical trials should be conducted to evaluate the benefits of pirlindole. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Depressive symptoms and executive functioning in stroke patients: A follow-up study International Journal of Geriatric Psychiatry, 10/27/10 Predictors of incident major depression in diabetic outpatients with subthreshold depression Diabetic Medicine, 10/26/10 Atherosclerosis and incident depression in late life Archives of General Psychiatry, 11/05/10 ©1999-2010 MDLinx, Inc.

 

Your Article Summary Deep brain stimulation in the treatment of depression (>> click to go to the journal's website) Acta Psychiatrica Scandinavica, 10/26/10

Blomstedt P et al. – Deep brain stimulation (DBS) is a promising treatment for therapy–refractory major depressive disorder (MDD). The published experience is, however, limited, and the method is at present an experimental therapy. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Depressive symptoms during the first chemotherapy cycle predict mortality in patients with advanced non-small cell lung cancer Supportive Care in Cancer, 09/24/10 Predictors of incident major depression in diabetic outpatients with subthreshold depression Diabetic Medicine, 10/26/10 Influence of depression symptoms on serum tumour necrosis factor-alpha of patients with chronic low back pain Arthritis Research & Therapy, 10/15/10

 

Your Article Summary Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment (>> click to go to the journal's website) CNS Neuroscience & Therapeutics, 10/29/10

Spadoni G et al. – Well–documented effects of agomelatine suggest that this MLT agonist offers an attractive alternative for the treatment of depression, combining efficacy with a favorable side effect profile. Despite a large number of high affinity nonselective MLT receptor agonists, only limited data on MT1 or MT2 subtype–selective compounds are available up to now. Administration of the MT2–selective agonist IIK7 to rats has proved to decrease NREM sleep onset latency, suggesting that MT2 receptor subtype is involved in the acute sleep–promoting action of MLT; rigorous clinical studies are needed to demonstrate this hypothesis. Further clinical candidates based on selective activation of MT1 or MT2 receptors are expected in coming years. Receive more summaries like this by joining MDLinx. We provide free daily digests of top journal articles in your field. >> Click here to choose your specialties.

Other articles in Internal Medicine >> Click here to see the complete list Efficacy and safety of doxepin 6 mg in a model of transient insomnia Sleep Medicine, 09/15/10 Persistent Insomnia in Chronic Hypnotic Users Presenting to a Sleep Medical Center: A Retrospective Chart Review of 137 Consecutive Patients The Journal of Nervous and Mental Disease, 10/26/10 Societal costs of insomnia Sleep Medicine Reviews , 10/25/10