Predicting the Outcome of
Antidepressants and Psychotherapy for Depression: A Qualitative, Systematic Review
Harvard Review of Psychiatry, 03/17/09
Van HL et al. - The relation between severity of depression and outcome appeared to be complex, precluding any straightforward inferences. Methods
- Overview of the consistency of findings on the association between sociodemographic factors and depression characteristics.
- Outcomes of pharmacotherapy, cognitive-behavioral therapy, and interpersonal/psychodynamic psychotherapy for major depression.
- No findings indicating that gender was associated with treatment outcome in the case of tricyclic antidepressants.
- Some indications that younger patients respond worse to tricyclics, whereas especially women appeared to have better outcomes with modern antidepressants (selective serotonin/norepinephrine reuptake inhibitors).
- Marital status may be related to better outcome in the case of antidepressants and cognitive-behavioral therapy.
- Longer duration of depression was identified as a negative predictor, most consistently in psychotherapy.
- In none of the treatment modalities was recurrence a negative predictor.
No comments:
Post a Comment