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Highlights of this issue Kimberlie Dean The British Journal of Psychiatry
2011;198 A5
http://bjp.rcpsych.org/cgi/
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*EDITORIALS*
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Assisted suicide: why psychiatrists should engage in the debate Matthew
Hotopf, William Lee, and Annabel Price The British Journal of Psychiatry
2011;198 83-84
http://bjp.rcpsych.org/cgi/
Questioning the neuroprotective hypothesis: does drug treatment prevent
brain damage in early psychosis or schizophrenia? Joanna Moncrieff The
British Journal of Psychiatry 2011;198 85-87
http://bjp.rcpsych.org/cgi/
The Movement for Global Mental Health Vikram Patel, Pamela Y. Collins, John
Copeland, Ritsuko Kakuma, Sylvester Katontoka, Jagannath Lamichhane, Smita
Naik, and Sarah Skeen The British Journal of Psychiatry 2011;198 88-90 *Open
access article*
http://bjp.rcpsych.org/cgi/
Equity of access to psychological therapies David A. Richards and Peter
Bower The British Journal of Psychiatry 2011;198 91-92
http://bjp.rcpsych.org/cgi/
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*REVIEW ARTICLES*
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Efficacy of mood stabilisers in the treatment of impulsive or repetitive
aggression: systematic review and meta-analysis Roland M. Jones, James
Arlidge, Rebecca Gillham, Shuja Reagu, Marianne van den Bree, and Pamela J.
Taylor The British Journal of Psychiatry 2011;198 93-98
http://bjp.rcpsych.org/cgi/
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*PAPERS*
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Policy initiative to improve access to psychological services for people
with affective and anxiety disorders: population-level analysis Meredith G.
Harris, Philip M. Burgess, Jane E. Pirkis, Tim N. Slade, and Harvey A.
Whiteford The British Journal of Psychiatry 2011;198 99-108
http://bjp.rcpsych.org/cgi/
Neuropathological correlates of late-life depression in older people Christos
Tsopelas, Robert Stewart, George M. Savva, Carol Brayne, Paul Ince, Alan
Thomas, Fiona E. Matthews the Medical Research Council Cognitive Function
and Ageing Study The British Journal of Psychiatry 2011;198 109-114
http://bjp.rcpsych.org/cgi/
Neuropsychological changes and treatment response in severe depression Katie
M. Douglas, Richard J. Porter, Robert G. Knight, and Paul Maruff The British
Journal of Psychiatry 2011;198 115-122
http://bjp.rcpsych.org/cgi/
Quantifying the effect of early retirement on the wealth of individuals with
depression or other mental illness Deborah J. Schofield, Rupendra N.
Shrestha, Richard Percival, Simon J. Kelly, Megan E. Passey, and Emily J.
Callander The British Journal of Psychiatry 2011;198 123-128
http://bjp.rcpsych.org/cgi/
Life stress, 5-HTTLPR and mental disorder: findings from a 30-year
longitudinal study David M. Fergusson, L. John Horwood, Allison L. Miller,
and Martin A. Kennedy The British Journal of Psychiatry 2011;198 129-135
http://bjp.rcpsych.org/cgi/
Coming home may hurt: risk factors for mental ill health in US reservists
after deployment in Iraq Lyndon A. Riviere, Athena Kendall-Robbins, Dennis
McGurk, Carl A. Castro, and Charles W. Hoge The British Journal of
Psychiatry 2011;198 136-142
http://bjp.rcpsych.org/cgi/
Mental health of the non-heterosexual population of England Apu Chakraborty,
Sally McManus, Terry S. Brugha, Paul Bebbington, and Michael King The
British Journal of Psychiatry 2011;198 143-148
http://bjp.rcpsych.org/cgi/
Overcrowding in psychiatric wards and physical assaults on staff:
data-linked longitudinal study Marianna Virtanen, Jussi Vahtera, G. David
Batty, Katinka Tuisku, Jaana Pentti, Tuula Oksanen, Paula Salo, Kirsi Ahola,
and Mika Kivimäki The British Journal of Psychiatry 2011;198 149-155
http://bjp.rcpsych.org/cgi/
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*Correspondence*
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Continuing lack of evidence for the psychotic subtyping of PTSD Elisa
Brietzke, André Zugman, Elson Asevedo, Rodrigo Mansur, and Graccielle
Rodrigues da Cunham The British Journal of Psychiatry 2011;198 156
http://bjp.rcpsych.org/cgi/
Authors reply: Brandon A. Gaudiano and Mark Zimmerman The British Journal
of Psychiatry 2011;198 156
http://bjp.rcpsych.org/cgi/
Is transference-focused psychotherapy really efficacious for borderline
personality disorder? Nikolaus Kleindienst, Bertram Krumm, and Martin Bohus The
British Journal of Psychiatry 2011;198 156-157
http://bjp.rcpsych.org/cgi/
Author s reply: Stephan Doering The British Journal of Psychiatry 2011;198
157
http://bjp.rcpsych.org/cgi/
Ziprasidone and the relative risk of diabetes Douglas Vanderburg, Denis
Keohane, Onur N. Karayal, and Elizabeth Pappadopulos The British Journal of
Psychiatry 2011;198 157-158
http://bjp.rcpsych.org/cgi/
Authors reply: Lars Vedel Kessing and Per Kragh Andersen The British
Journal of Psychiatry 2011;198 158
http://bjp.rcpsych.org/cgi/
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*Correction*
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Correction The British Journal of Psychiatry 2011;198 159
http://bjp.rcpsych.org/cgi/
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*Book reviews*
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Contemporary Directions in Psychopathology: Scientific Foundations of the
DSM-V and ICD-11 David Goldberg The British Journal of Psychiatry 2011;198
160
http://bjp.rcpsych.org/cgi/
Psychotherapy Is Worth It: A Comprehensive Review of the
Cost-Effectiveness Frank
Margison The British Journal of Psychiatry 2011;198 160-161
http://bjp.rcpsych.org/cgi/
Psychiatry: An Evidence-Based Text Floriana Coccia The British Journal of
Psychiatry 2011;198 161
http://bjp.rcpsych.org/cgi/
Chronotherapeutics for Affective Disorders: A Clinician s Manual for Light
and Wake Therapy John M. Eagles The British Journal of Psychiatry 2011;198
161-162
http://bjp.rcpsych.org/cgi/
Oxford Textbook of Women and Mental Health Fiona L. Mason The British
Journal of Psychiatry 2011;198 162
http://bjp.rcpsych.org/cgi/
Schizophrenia: Who Cares? Leonard Fagin The British Journal of Psychiatry
2011;198 162-163
http://bjp.rcpsych.org/cgi/
Behavioural Activation for Depression: A Clinician s Guide Linda Gask The
British Journal of Psychiatry 2011;198 163
http://bjp.rcpsych.org/cgi/
Supportive Care for the Person with Dementia Jan R. Oyebode The British
Journal of Psychiatry 2011;198 163-164
http://bjp.rcpsych.org/cgi/
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*Extras*
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There used to be surgeons too . . . - extra Shabbir Amanullah The British
Journal of Psychiatry 2011;198 87
http://bjp.rcpsych.org/cgi/
Gérard de Nerval - the man who walked lobsters - fallen stars Raymond
Cavanaugh, Jr The British Journal of Psychiatry 2011;198 108
http://bjp.rcpsych.org/cgi/
Morbid jealousy may have been recognised in the Old Testament - psychiatry
in the Old Testament George Stein The British Journal of Psychiatry 2011;198
142
http://bjp.rcpsych.org/cgi/
Versions of a poem by Hesse - poems by doctors Adam Polnay The British
Journal of Psychiatry 2011;198 155
http://bjp.rcpsych.org/cgi/
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*From the Editor's desk*
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From the Editor s desk Peter Tyrer The British Journal of Psychiatry
2011;198 166
http://bjp.rcpsych.org/cgi/
*BJP Online -- Highlights of the Current Issue*
February 2011; Vol. 198, No. 2
The complete Table of Contents for the current issue is available online at:
http://bjp.rcpsych.org/content/vol198/issue2/<http://bjp.rcpsych.org/content/vol198/issue2/?highlights>
The following content is available online at:
http://bjp.rcpsych.org/cgi/content/full/198/2/A5<http://bjp.rcpsych.org/cgi/content/full/198/2/A5?highlights>
Highlights of this issue * Kimberlie Dean *
*Depression: neuropathology, neuropsychology and the impact of early
retirement*
In a community-derived sample of individuals without dementia as assessed
during life, Tsopelas *et al* (pp.
109-114<http://bjp.rcpsych.org/cgi/content/full/198/2/109>
) examined the relationship between the presence of late-life depression and
a range of neuropathological correlates. Depression was associated with the
presence of subcortical Lewy bodies, neuronal loss in the hippocampus and
some subcortical regions, but not with cerebrovascular or Alzheimer
pathology. Douglas *et al* (pp.
115-122<http://bjp.rcpsych.org/cgi/content/full/198/2/115>)
examined neuropsychological changes in relation to treatment response in a
sample of in-patients with severe depression and found that, despite
significant impairment at baseline, most measures failed to differentiate
treatment responders from non-responders at either 10-14 days or 6 weeks.
The only positive findings were for simple reaction time, verbal working
memory and recognition of angry facial expressions when measured at 6 weeks.
The authors concluded that their findings cannot support the hypothesis that
neuropsychological tasks identify early changes in individuals with severe
depression who will go on to respond to treatment. Schofield *et al* (pp.
123-128 <http://bjp.rcpsych.org/cgi/content/full/198/2/123>) found that
individuals in Australia who retire early owing to depression or other
mental illness are disadvantaged in terms of wealth accumulation compared
with those of the same age, gender and education who remain within the
labour force without ill health. They also found that the former are more
likely to have wealth in the form of cash assets rather than high-growth
asset investments. The authors comment on the impact of such disadvantage
for future living standards, health status, quality of life and the
consequences for the state in terms of financial burden.
*The impact of stressful life events and conflict deployment on mental
health*
The role of the serotonin transporter gene in moderating the association
between stressful life events and risk of depression has recently been
called into question by the negative findings of two systematic reviews.
Fergusson *et al* (pp.
129-135<http://bjp.rcpsych.org/cgi/content/full/198/2/129>
) utilised data from a 30-year New Zealand birth cohort, the Christchurch
Health and Development Study, to test the hypothesis again and found no
evidence to support a gene x environment interaction between the s alleles
of 5-HTTLPR and increased responsivity to life stressors, after
considering four
mental health outcomes observed at four ages using 13 measures of
life-course stress. Reservists deployed to both the Iraq and Afghanistan
conflicts have been found to be at greater risk for developing mental health
problems than their regular soldier counterparts. In a US study by Riviere *et
al* (pp. 136-142 <http://bjp.rcpsych.org/cgi/content/full/198/2/136>),
unique post-deployment social and material concerns were found to be
associated with depression and post-traumatic stress disorder (PTSD). For
example, job loss was associated with depression and PTSD at 12 months
post-deployment (at 3 months also for depression), and the negative effect
of employment absence on co-workers was found to be associated with PTSD at
both time points.
*Aggression: treatment with mood stabilisers and risk of assault on
in-patient staff*
In a systematic review and meta-analysis by Jones *et al* (pp.
93-98<http://bjp.rcpsych.org/cgi/content/full/198/2/93>),
the pooled analysis indicated a significant reduction in the
frequency/severity of repetitive or impulsive aggressive behaviour among
those treated with mood stabilisers *v*. placebo in adults without
intellectual disability, organic brain disorder or psychosis. However, the
authors also found evidence of substantial heterogeneity among studies and
when the analysis included only those studies assessed as having a low risk
of bias, no significant effect on aggression was found. In a data-linked
longitudinal study of 13 acute psychiatric hospitals in Finland, Virtanen *et
al* (pp. 149-155 <http://bjp.rcpsych.org/cgi/content/full/198/2/149>)
found that
ward overcrowding was associated with an increased risk of violence towards
staff but not of violence towards ward property. The authors also found a
high prevalence of overcrowding, with 46% of hospital staff working in wards
with a more than 10% excess bed occupancy rate.
*Population studies of mental health and access to services*
Using data from the UK Adult Psychiatric Morbidity Survey 2007, Chakraborty
*et al* (pp. 143-148 <http://bjp.rcpsych.org/cgi/content/full/198/2/143>)
found that those who self-identified as non-heterosexual were more likely to
report a range of mental health problems and were more likely to have had
primary or community care contact for mental health reasons during the
previous year. In addition, discrimination on the grounds of sexual
orientation was found to predict some neurotic disorder outcomes. Using data
from another population-based survey conducted in 2007, this time in
Australia, Harris *et al* (pp.
99-108<http://bjp.rcpsych.org/cgi/content/full/198/2/99>)
examined the impact of the Better Access programme, a publicly funded
initiative designed to improve access to psychological services for
individuals with affective and anxiety disorders. In contrast to concerns
raised about the programme, the authors found no evidence that Better Access is
over-servicing individuals without need or contributing to social
inequalities in mental healthcare.
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