* baclofen -nul in alcoolism
Efficacy and safety of baclofen for alcohol dependence: A randomized, double-blind, placebo-controlled trial
Garbutt JC et al. – The purpose of the present study was to test the efficacy and tolerability of baclofen in alcohol dependence in the United States. Baclofen, a GABAB agonist, represents a possible new pharmacotherapeutic approach to alcohol dependence. Despite encouraging preclinical data and prior positive clinical trials with baclofen in Italy, the current trial did not find evidence that baclofen is superior to placebo in the treatment of alcohol dependence.