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Poyurovsky M, et al. – The authors evaluated whether mirtazapine is also effective for akathisia induced by the partial dopamine D2 receptor agonist aripiprazole. Low–dose mirtazapine was well tolerated, and mild sedation, the only side effect (three patients), was transient. A large–scale controlled investigation is warranted to substantiate clinical utility of mirtazapine for akathisia induced by aripiprazole and other second–generation antipsychotics.
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