1 Evaluarea antipsihoticelor(BJP)
To assess the clinical relevance of findings in the literature.
A systematic review identified studies of antipsychotics that used the Brief Psychiatric Rating Scale (BPRS) and Positive and Negative Syndrome Scale (PANSS). A published method of translating these into Clinical Global Impression – Change scale (CGI–C) scores was used to measure clinical relevance.
In total 98 data-sets were included in the BPRS analysis and 202 data-sets in the PANSS analysis. When aggregated scores were translated into notional CGI–C scores, most drugs reached 'minimal improvement' on the BPRS, but few reached that level for PANSS. This was true of both first- and second-generation drugs, including clozapine. Amisulpride and olanzapine had better than average CGI–C scores.
ConclusionsOur findings show improvements of limited clinical relevance. The CGI–C scores were better for the BPRS than for the PANSS.
April 8, 2011 — For the first time, researchers have found that peripheral blood mononuclear cells express amyloid precursor protein
<p>April 21, 2011 (Honolulu, Hawaii) — A new analysis of data from the Framingham Heart Study suggests that survivors of cancer,
<b>Conclusions:</b> This indirect database analysis suggested that paliperidone ER 6–12 mg/day may be more efficacious than risperidone
April 14, 2011 — A meta-analysis of 61 studies that looked at the relationship between cancer and antidepressant use shows a "small
Living in love and living in fear create opposite effects in the body and the mind. I'd just like to
Chiar daca este o afectiune psihiatrica, sarcina falsa (isterica) cunoscuta si sub numele de pseudosarcina, genereaza multe simptome si
Statistic, sarcina falsa (isterica) apare in 1-6 cazuri la fiecare 22.000 de nasteri si afecteaza femei cu o dorinta puternica de a ramane
Principalul mecanism de producere a sarcinii false (isterice) implica dezechilibre hormonale care duc la secretia inadecvata a unor hormoni
Unele semne de pseudosarcina pot aparea si la barbatii care sufera de sindromul Couvade, care presupune o relatie stransa cu o femeie
Orice test de sarcina pe baza hCG infirma prezenta sarcinii.
9. vitamina D
Lithium is an established treatment for affective disorderswith good evidence of antisuicidal properties. Alzheimer'sdisease rates are relatively reduced in patients with bipolardisorder on lithium and a recent trial of lithium in amnesticminimal cognitive impairment is indicative of potential benefits.This should stimulate further, larger-scale studies.
11. industria farmaceutica
Fifty years ago pharmacological discoveries transformed psychiatry but progress since then has been relatively slow and thereis unease about the role of industry. Despite this, the possibilities of pharmacological treatment have improved in recent years but exploiting developments for the benefit of patients requirespsychotherapeutic skill as well as a high level of scientific knowledge.
12. prevenirea tb.afective(BJP)
Psychological interventions for mood disorders can be divided into 'skilled' and 'simple'. Psychoeducationbelongs to the latter group: a simple and illness-focused therapy with prophylactic efficacy in all major mood disorders. Successful implementation of psychoeducation requires a proper setting, including open-door policy, team effort and empowerment of the therapeutic alliance.
13. vitamina D3
14. screningul nu creste riscul de suicid ( BLP)
15. tratamentul bulimiei
Psychological treatments for bulimia and depressionEven when treatments have demonstrated efficacy in a specific disorder, the optimal manner in which to apply them can still remain unclear. Mitchell et al (pp. 391–397) studied a stepped care approach to treating bulimia – starting with a self-help technique, then going on to fluoxetine, and finally using cognitive–behavioural therapy (CBT), if patients are not responding to the earlier treatment. They found that this stepped care was superior to standard CBT augmented with fluoxetine at 1 year follow-up. At the end of treatment, a brief supervised self-help version of CBT, delivered by less experienced therapists and augmented with fluoxetine treatment, was as effective as a longer period of traditional CBT by expert therapists, with added fluoxetine. The stepped care approach was also likely to be more cost-effective. The value of family intervention in depression is highlighted by Shimazu et al (pp. 385–390): they found that time to relapse was significantly reduced after four sessions of a family psychoeducation intervention. Interestingly, these effects did not appear to be mediated by changes in familial expressed emotion and were achieved without the patient attending the sessions. An accompanying editorial by Colom (pp. 338–340) reviews the benefits of psychoeducation and also refers to the important, but often neglected, necessary multiple components of effective psychoeducation. He is clear that psychoeducation is not the mere provision of educational material, general guidance on prevention, or advice on crisis management, but is a more interactive process of developing a shared understanding of the management of a patient s condition. Towards this end, he sets out some of the necessary environmental conditions for effective psychoeducation to flourish.