Asherson P, et al. – In this study, authors found that ATX had a clinically significant effect in adults with ADHD, with reductions in core symptoms and clinically meaningful responder rates. Methods
They performed an integrated analysis of all Eli Lilly–sponsored, randomized, double–blind, placebo–controlled studies of ATX in adults with ADHD completed as of May 2012.
Individual patient data were pooled from six short–term (10–16 week) studies (1961 patients) and three longer–term (six–month) studies (1413 patients).
In the short–term analysis, ATX patients achieved a significantly greater mean reduction in ADHD symptoms than placebo patients (–12.2 vs –8.1; Conners' Adult ADHD Rating Scale–Investigator–Rated: Screening Version (CAARS–Inv: SV); p<0 data-blogger-escaped-.001="" data-blogger-escaped-li="">
In the longer–term analysis, respective improvements after six months were –13.2 vs –9.7 (p<0 data-blogger-escaped-.001="" data-blogger-escaped-li="">
Response rates at study endpoints for ATX vs placebo, based on CAARS–Inv: SV improvement ≥30% and Clinical Global Impressions of ADHD–Severity (CGI–ADHD–S) ≤3 were 34.8% vs 22.3% in the short–term and 43.4% vs 28.0% after six months, and CAARS–Inv: SV improvements ≥40% were 41.3% vs 25.3% in the short–term and 44.0% vs 31.4% after six months (all p<0 data-blogger-escaped-.001="" data-blogger-escaped-li="">
Istoric In Romania, in vremea comunismului, pshiatrii au fost incadrati in APR, ramura a celorlalte ramuri medicale.Dupa 1989 APR si-a coninuat prezenta, fiind in continuare condusa de urmasii lui Predescu, Gorgos, Angheluta & co. APR se face vinovat in fata istoriei printr-o selectie mafiotica care a coborit psihiatria romaneasca la un instrument de persecutie a regimului fata deorice aspiratie de innoire,de respingerea a numeroase valori care n-au incaput in breasla si au trebuit sa emigreze sau sa fie marginalizati, perspectiveneavind decit cei hiperadaptati la teroarea raului. Persecutiile fata de psihiatrii si chiar fata de unii bolnavi sunt cunoscute. Text integral