Rosell DR, et al. – The study of schizotypal personality disorder (SPD) is important clinically, as it is understudied, challenging to treat, often under–recognized or misdiagnosed, and associated with significant functional impairment. In this review authors discuss recent findings of SPD related to epidemiology and functional impairment, heritability and genetics, working memory and cognitive impairments, social–affective disturbances, and neurobiology. SPD also represents an intermediate schizophrenia–spectrum phenotype, and therefore, can provide a better understanding of the genetics, pathogenesis, and treatment of related psychotic illnesses.
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